Thursday, 21st February Lorne Infection and Immunity 2019

Alpha methodology is a No-Wash bead based assay which is utilised in immunological and inflammation research for, (1) Cytokine profiling, biomarker detection assays associated with inflammation, and immune response and repair, (2) Immunogenicity functional assays that enable direct detection and quantification of antibodies in serum samples, (3) Cellular kinase detection that directly measures endogenous levels of phosphorylated cellular proteins in cell and tissue lysates. 
Join PerkinElmer for a Breakfast workshop and learn how this unique no wash homogenous bead-based method will reduce your time to results and make running assays the most stress free part of your day. 

To sign up for this workshop, return to your dashboard and select the add-on 'Thursday Breakfast Workshop'.

• Intravenous Immunization with BCG Induces a High Frequency of Tissue Resident T cells and Prevents Mycobacterial tuberculosis Infection in Non-Human Primates - Robert Seder
• Learnings from experimental human malaria infection studies - James McCarthy
• Immune reconstitution and antiviral drug resistance in haematopoietic stem cell transplant recipients with reactivated human cytomegalovirus infection - Barry Slobedman
• Busting a century old myth - new insights into the immunopathogenesis of rheumatic heart disease and potential for immunotherapy - Natkunam Ketheesan
• Exploring bacterial resistance with antibiotic-derived fluorescent probes - Mark A. T. Blaskovich

• Intracellular DNA sensing in health and disease - Andrea Ablasser
• Exploring the immuno-metabolome of neonatal sepsis  - Andrew Currie
• Friend or foe? Macrophage control of influenza A virus replication - Sarah L Londrigan
• Membrane phospholipid targeting by defensins induces fungal and tumour cell lysis - Mark D Hulett
• Direct regulation of dendritic cell functions by the immune checkpoint PD-1 - Christophe Macri
• A novel universal transmembrane adaptor for Toll-like receptors promotes selective pro-inflammatory responses - Lin Luo
• Post-translational Regulation of Inflammasome-associated IL-1β - James Vince

• Mechanisms for suppressing pro-inflammatory cell death during development - Kim Newton
• Battle to the end: how the interplay of host and pathogen metabolism regulates innate immune interactions in fungal infections - Ana Traven
• Transcription factor T-bet in B cells controls germinal centre dark zone-light zone polarization and enhances antibody affinity maturation in response to malaria     - Diana S Hansen
• Interpreting the visual metaphor of the Candida albicans cell wall - Megan D Lenardon

• Zika virus and its antibody complex structures  - Shee-Mei Lok
• Chronic medical conditions and severe influenza virus infections - Kirsty Short
• Engineered resistance to arboviruses in Aedes aegypti - Prasad N Paradkar
• Identification of a novel innate defence mechanism in neurons against Rabies virus. - Vinod Sundaramoorthy

• Hepatitis B virus e antigen abrogates early host immunity - Gregor Ebert
• Bifunctional purine biosynthesis enzyme GAR synthetase/AIR synthetase as an antifungal target - Sheena Chua
• Interferon ε is expressed in human and mouse intestinal epithelium and prevents from exacerbated intestinal inflammation - Eveline D. de Geus
• Programmed Cell Death During Murine Norovirus Infection - Joshua Deerain
• Discovery of the molecular machinery regulating antigen presentation of bacterial metabolites by MR1 - Hui Jing Lim
• The epigenetic regulation by histone modifiers determines B cell fate decisions during acute and chronic infections. - Andrea Di Pietro
• Necroptosis directly induces full-length bioactive IL-33 release - Inbar Shlomovitz
• Dynamics of polymorphism in a leading Plasmodium falciparum vaccine candidate -Reticulocyte Binding Protein Homologue 5 (RH5) - Myo Naung
• Dissecting a machinery that folds virulence proteins in Salmonella Typhimurium - Pramod Subedi
• Investigation of the mechanism of action of a novel class of anti-malarials - Matthew P Challis
• The impact of age on complement-fixing antibodies targeting P. vivax MSP3a - Damian Oyong
• New roles for myb in mature granulocytes - Kirsten Fairfax

• RP105 regulates LPS-induced TLR4 endocytosis and Type I IFN responses - Thomas E Schultz
• Antifungal surface coatings: an investigation into the mechanism of action of surface-grafted caspofungin - Stephanie Lamont-Friedrich
• ‘Ionobiotics’ - A new therapeutic approach to combat antibiotic resistant pathogens - David MP De Oliveira
• Superinfection exclusion can prevent alphavirus infection in Aedes mosquitoes - Mathilde LAURETI
• Mice expressing human Proteinase 3 show sustained neutrophil infiltration and a defect in the resolution of inflammation - Katherine Martin
• Characterisation of bacterial effector kinases from enteropathogenic Escherichia coli - Georgina L Pollock
• Dendritic cell paralysis post systemic inflammation: The cytokine aspect - Mitra Ashayeri-Panah
• Delayed death in the malaria parasite: prenylation dependant disruption of intracellular trafficking  - Kit Kennedy
• Characterisation of a family of novel secreted bacterial glycosyltransferases - Cristina Giogha
• The structural and molecular insights into CD1d-glycolipid and natural killer T cell receptor recognition - Praveena Thirunavukkarasu
• Ebola virus VP24 uses a dual strategy of karyopherin-dependent mechanisms to suppress STAT3 signalling - Angela R Harrison
• A dysregulated IL-1β-GM-CSF axis in acute rheumatic fever that is limited by hydroxychloroquine   - Man Lyang Kim
• Legionella clearance from the lung is affected by cigarette smoke - Markus Fleischmann

• Adaptive immune surveillance by human γδ T cells in microbial infection - Martin S Davey
• Alternative splicing in apicomplexan parasites - Stuart A Ralph
• The bacterial pathogen Listeria monocytogenes: towards a complete understanding of its physiology and its virulence - Pascale Cossart

• Mechanistic insights into hyperinflammation caused by XIAP deficiency - Kate Lawlor
• Investigating alternative splicing in apicomplexan parasites - V Vern Lee
• Mechanism of surface MHC II regulation - Haiyin Liu
• The evolution and phylogenetic analysis of Ross River virus - Wenjun Liu
• Sub-population characterisation of human phagocytes during Mycobacterium tuberculosis infection by flow-FISH - Rachel J Lundie
• Shark antibodies and their role in targeting bacterial adhesins: alternatives against urinary tract infections - Gabriela Constanza Martinez Ortiz
• Ontogeny of the immune response in the chicken chorioallantoic membrane (CAM) - Meg McDonald
• Regulation of alternative splicing in Plasmodium falciparum - Emma McHugh
• DNA barcoding and metagenomics as basis of precision-based diagnosis of mycoses - Wieland Meyer
• Induction and investigation of inhibitory antibodies towards Salmonella enterica serovar Typhimurium - Joshua N Monteith
• Viral hijacking of the nucleolar DNA-damage response machinery: a novel mechanism to regulate host cell biology - Stephen M Rawlinson
• Study of innate immune responses to Semliki Forest virus infection in immature and mature neurons - Divya Narayanan
• Characterisation of Bromodomain protein 3 in Plasmodium falciparum - Hanh Nguyen
• Infection-induced vascular dysfunction drives mycobacterial infection - Stefan H Oehlers
• Characterising the role of guanylate binding proteins in tuberculosis - Nashied Peton
• The Prevalence of Inhibitory Antibodies in an Australian Cystic Fibrosis Cohort - Amy Pham
• RNA stability in alphavirus infected cells - Damien Phan
• Fas signalling in immune defence against the intestinal pathogen, Citrobacter rodentium. - Pin Shie Quah
• High spare respiratory capacity is a key feature of virtual memory CD8 T cells, which is augmented by age, infection and IL-15 signaling. - Kylie Quinn
• Role of IFNg induced genes in cell autonomous defence against Legionella - Linda Rafeld
• Differences in metabolic risk factors for tuberculosis in close contacts with diabetes from two ethnicities impacting M. tuberculosis growth in peripheral blood mononuclear cells - Katharina Ronacher
• How pathogenic bacteria fold disulphide bond–containing virulence factors   - Carlos Fernando Santos Martin
• How metabolism determines the outcome of adoptive T cell therapy - Christina Scheffler
• Characterisation of a monoclonal antibody towards the N-terminal hypervariable region 1 (HVR1) and epitope I of Hepatitis C Virus Glycoprotein E2 - Felicia Schlotthauer
• Understanding neutrophil-Candida interactions using a panel of clinical isolates - Madhu Shankar
• A longitudinal study on the effect of plasmapheresis on the Pseudomonas aeruginosa population in the lung - Emma Sheehan
• IFNg and Toll-like Receptor signalling induces macrophage cell death  - Daniel Simpson
• The investigation of antigen-only nanocapsules as a novel vaccine platform. - Ivana Skakic
• The role of O-GlcNAcylation in dendritic cell function and immunity - Ilknur Spring
• The cryptococcus neoformans saga   - Christina Stephenson
• Characterisation of molecular mechanisms of macrophage-mediated zinc toxicity and subversion of this antimicrobial pathway by uropathogenic E. coli   - Claudia J Stocks
• Effect of corticosteroid treatment on intrahost virus dynamics and immune response in a rabbit model of West Nile virus infection - Willy W Suen
• A longitudinal study of γδ T cell subsets post lung transplant: Potential players in immunity to cytomegalovirus   - Lucy C Sullivan
• Ubiquitination and artemisinin resistance in Plasmodium falciparum - Madel Tutor
• Chikungunya virus undergoes genomic bottleneck during Aedes albopictus infection - Ravi kiran Vedururu
• The membrane-associated RING-CH (MARCH) 8 ubiquitin ligase is a restriction factor against influenza virus and respiratory syncytial virus. - Fernando Villalon-Letelier
• Identification of the Salmonella-derived MHC-II immunopeptidome reveals antigen selection mechanisms by CD4⁺ T cells against a complex bacterial pathogen - Nancy Wang
• Roles of the YEATS domain histone acylation reader Taf14 in morphogenesis, stress responses, and virulence of the fungal pathogen Candida albicans - Qi Wang
• The mechanisms underpinning antibody-mediated serum resistance of Pseudomonas aeruginosa.  - Timothy J Wells
• Salmonella Typhimurium induces cIAP degradation in macrophages in a SPI-1 dependent manner - Madeleine A Wemyss
• Investigating the role of protein kinase A in Plasmodium falciparum infection - Mary-Lou Wilde
• Purification of Plasmodium knowlesi merozoites: a comparative tool to study invasion biology and therapeutic targets of human pathogenic malaria parasites. - Danny Wilson
• The role of Flt3 in dendritic cells - Kayla R Wilson
• Purine metabolism as an antifungal target - Maha Wizrah
• Understanding the mechanisms that drive virulence and failure of antifungal therapy in the human yeast pathogen Candida albicans - Ka Pui Sharon Yau
• Helicobacter pylori growth stage determines the production, protein content and biological functions of outer membrane vesicles. - Lauren Zavan
• Analysis of extracellular vesicles generated from monocytes under conditions of lytic cell death - Amy A Baxter